BDBM50060033 3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine::CHEMBL97597

SMILES CC1CCN(CC1)C(=O)C(Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=NXVHWZWNOYBQDB-UHFFFAOYSA-N

Data  9 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50060033   

TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against bovine thrombin expressed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:The compound was evaluated in vitro for the thrombin inhibition.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  140nMAssay Description:Inhibitory activity against bovine trypsin expressed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  140nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibitory activity against human urokinase plasminogen activator expressed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibitory activity against bovine coagulation factor X expressed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataIC50:  640nMAssay Description:In vitro thrombin inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro trypsin inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed