BDBM50060444 3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole::CHEMBL117633

SMILES C(CN1CCN(CCc2ccccc2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key InChIKey=NRYCUQFVARKWSL-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060444   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060444(3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060444(3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4...)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060444(3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4...)
Affinity DataEC50:  1.70nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060444(3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]-5-HT binding to the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060444(3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4...)
Affinity DataIC50:  166nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060444(3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4...)
Affinity DataEC50:  0.900nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed