BDBM50060711 (S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide; hydrochloride::CHEMBL555333

SMILES NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)CC(C2CCCCC2)C2CCCCC2)CC1

InChI Key InChIKey=CZXNACPIFMZJFW-QNAFOZIXSA-N

Data  6 KI  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060711   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060711((S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  14nM Koff:  2.30E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060711((S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  2.50E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060711((S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  8.40E+4nMAssay Description:Inhibitory activity against serine protease TPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060711((S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibitory activity against serine protease plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060711((S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  1.76E+5nMAssay Description:Inhibitory activity against serine protease plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060711((S)-1-(3,3-Dicyclohexyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibitory activity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed