BDBM50061255 1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)-butan-1-one::1-(4-fluorophenyl)-4-(3-phenyl-8-aza-bicyclo[3.2.1]octan-8-yl)butan-1-one::CHEMBL340816::CHEMBL553417

SMILES Fc1ccc(cc1)C(=O)CCCN1C2CCC1CC(C2)c1ccccc1

InChI Key InChIKey=LECUUDCCVOYUHG-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50061255   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  34.1nMAssay Description:Sigma-1 binding assay was done in guinea pig membranes by labelling the binding site with [3H]-(+)-pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  88.5nMAssay Description:Binding affinity of the compound for serotonin transporter was determined in rat cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  106nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  124nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  124nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  129nMAssay Description:Binding affinity for dopamine transporter was determined in rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  177nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  177nMAssay Description:Binding affinity for dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  414nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVesicular acetylcholine transporter(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  594nMAssay Description:Binding to vesicular acetylcholine transporter of torpedo synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  974nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  1.07E+3nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed