BDBM50062297 (R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-pyridin-4-yl-ethyl}-2-isobutyl-succinamide::CHEMBL302311

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](Cc1ccncc1)C(=O)NCCc1ccc(O)cc1

InChI Key InChIKey=LUZFASJCLDTWLF-TZIWHRDSSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062297   

TargetNeutrophil collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062297((R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)...)
Affinity DataKi:  0.330nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062297((R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)...)
Affinity DataKi:  1.70nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062297((R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed