BDBM50062374 (2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL312977

SMILES Fc1ccc(cc1)[C@@H]1CC2CCC(N2)[C@@H]1COc1ccc2OCOc2c1

InChI Key InChIKey=HAHQKXHPHSTOFJ-PZZKWDHKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062374   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062374((2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50:  56nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062374((2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062374((2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50:  28nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed