BDBM50063100 6'-trifluoromethylspiro[cyclohexane-1,2'-(1',2',3',4',8',9'-hexahydropyrido[3,2-g]quinoline)]-8'-one::CHEMBL345854

SMILES FC(F)(F)c1cc(=O)[nH]c2cc3NC4(CCCCC4)CCc3cc12

InChI Key InChIKey=FJUPCQHIHYXXFT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063100   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063100(6'-trifluoromethylspiro[cyclohexane-1,2'-(1',2',3'...)
Affinity DataKi:  9nMAssay Description:Binding affinity for human androgen receptor in transiently-transfected COS-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063100(6'-trifluoromethylspiro[cyclohexane-1,2'-(1',2',3'...)
Affinity DataIC50:  1.83E+3nMAssay Description:Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063100(6'-trifluoromethylspiro[cyclohexane-1,2'-(1',2',3'...)
Affinity DataIC50:  35nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed