BDBM85043 CAS_149017-66-3::CHEMBL69234::NSC_6093163::PPADS
SMILES Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O
InChI Key InChIKey=PNFZSRRRZNXSMF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 85043
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
TargetP2X purinoceptor 2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X6 receptor (mutant type)More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (mutant type)More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at human P2X4 receptor (mutant type)More data for this Ligand-Target Pair
TargetP2X purinoceptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at mouse P2X4 receptor (mutant type)More data for this Ligand-Target Pair
TargetP2X purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X6 receptor (wild type)More data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Antagonist activity at mouse P2X1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X3) at 10 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 5 (P2X5)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 4 (P2Y4)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)More data for this Ligand-Target Pair
Affinity DataEC50: 6.20E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 99nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X3) at 10 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against phospholipase C coupled rat P2Y purinoceptor 12 (P2Y12)More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 1.20E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat receptor P2X purinoceptor 2 (P2X2) at 30 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Human)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataEC50: 1.00E+4nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
TargetP2X purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 6 (P2X6 )More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 240nMAssay Description:Antagonist activity at human P2X3 receptorMore data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Rat)
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Max-Planck Institute For Experimental Medicine
Curated by PDSP Ki Database
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (wild type)More data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Wild turkey)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of 10 nM 2-MeSADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]-inositolMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 9.85E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 2.40E+5nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X3 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
Affinity DataEC50: 1.82E+4nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of rat erythrocytesMore data for this Ligand-Target Pair