BDBM50065469 2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamide::CHEMBL44246

SMILES NC(=N)NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1

InChI Key InChIKey=KUWBXRGRMQZCSS-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50065469   

TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataKi:  4.60nMAssay Description:In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of binding of [3H]-propionyl-NPY (1 nM) to Neuropeptide Y receptor type 1 in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding of [3H]-propionyl-NPY (1 nM) to Neuropeptide Y receptor type 2 in SMS-KAN cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of binding of [3H]-propionyl-NPY (1 nM) to Neuropeptide Y receptor type 5 in HEC-1-B cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataIC50:  17nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed