BDBM50066624 3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-methyl-pyridin-2-yloxy]-benzamide::CHEMBL81579

SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=O)c1F

InChI Key InChIKey=SQMDPBNOJWCMCP-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50066624   

TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  280nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  280nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  280nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant against bovine trypsin for general specificity against serine proteasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory potency was measured against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066624(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory potency was measured against bovine trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed