BDBM50067668 2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL134421

SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12

InChI Key InChIKey=ZEZOALAOUQCQQW-HAHDFKILSA-N

Data  3 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50067668   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity against human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataKi:  299nMAssay Description:Binding affinity against human glucocorticoid receptor expressed in SF-12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataKi:  2.66E+3nMAssay Description:Binding affinity against human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataEC50:  24.4nMAssay Description:Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataIC50:  737nMAssay Description:Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067668(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Affinity DataIC50:  650nMAssay Description:Inhibitory activity (IC50) against human androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed