BDBM50067671 5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL137103

SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12

InChI Key InChIKey=ZVALABNDJZPNNC-QRVIBDJDSA-N

Data  3 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50067671   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataKi:  173nMAssay Description:Binding affinity against human glucocorticoid receptor expressed in SF-12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataKi:  887nMAssay Description:Binding affinity against human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataIC50:  371nMAssay Description:Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataEC50:  15nMAssay Description:Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067671(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity (IC50) against human androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed