BDBM50067797 CHEMBL19080::L-37378::N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl)-acetamide::US11584714, Compound 1488
SMILES Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NCCc2ccccc2)c1=O
InChI Key InChIKey=PVDHYBJORRALSQ-UHFFFAOYSA-N
Data 19 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50067797
Affinity DataKi: 0.800nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of Thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human thrombin assessed as release of p-nitroanilide from chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
Affinity DataKi: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of human trypsin assessed as release of p-nitroanilide from chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibitory constant evaluated against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibitory activity of the compound against trypsin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6.25E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair