BDBM50067921 4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-yloxymethyl)-biphenyl-2-ylmethyl]-carbamoyl}-vinyl)-N-methyl-benzamide::CHEMBL140383

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCc2ccccc2-c2ccc(C)c(COc3cccc4ccc(C)nc34)c2C)cc1

InChI Key InChIKey=AFUNWCBOHPULNY-LTGZKZEYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067921   

TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical Ltd.

Curated by ChEMBL
LigandPNGBDBM50067921(4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-...)
Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCc2ccccc2-c2ccc(C)c(COc3cccc4ccc(C)nc34)c2C)cc1
Show InChI InChI=1S/C37H35N3O3/c1-24-12-20-31(26(3)33(24)23-43-34-11-7-9-28-17-13-25(2)40-36(28)34)32-10-6-5-8-30(32)22-39-35(41)21-16-27-14-18-29(19-15-27)37(42)38-4/h5-21H,22-23H2,1-4H3,(H,38,42)(H,39,41)/b21-16+
Affinity DataIC50: 2.60nMAssay Description:Inhibition of the specific binding of [3H]BK to human recombinant Bradykinin receptor B2 expressed in CHO cells.More data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Cavia porcellus)
Fujisawa Pharmaceutical Ltd.

Curated by ChEMBL
LigandPNGBDBM50067921(4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-...)
Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCc2ccccc2-c2ccc(C)c(COc3cccc4ccc(C)nc34)c2C)cc1
Show InChI InChI=1S/C37H35N3O3/c1-24-12-20-31(26(3)33(24)23-43-34-11-7-9-28-17-13-25(2)40-36(28)34)32-10-6-5-8-30(32)22-39-35(41)21-16-27-14-18-29(19-15-27)37(42)38-4/h5-21H,22-23H2,1-4H3,(H,38,42)(H,39,41)/b21-16+
Affinity DataIC50: 2.30nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair