BindingDB logo
myBDB logout

BDBM50068085 CHEMBL358284::{5-[1-(1-Bromo-naphthalen-2-yl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid

SMILES: OC(=O)CN1C(=S)S\C(=C/c2ccc3ccccc3c2Br)C1=O

InChI Key: InChIKey=PDKGJWACKWSPEQ-GHXNOFRVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068085   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase (ALR2)


(Bos taurus (Cattle))
BDBM50068085
PNG
(CHEMBL358284 | {5-[1-(1-Bromo-naphthalen-2-yl)-met...)
Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc3ccccc3c2Br)C1=O
Show InChI InChI=1S/C16H10BrNO3S2/c17-14-10(6-5-9-3-1-2-4-11(9)14)7-12-15(21)18(8-13(19)20)16(22)23-12/h1-7H,8H2,(H,19,20)/b12-7-
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



EP811-CNRS

Curated by ChEMBL


Assay Description
Evaluated in vitro for the inhibition of Aldose reductase.


J Med Chem 41: 4706-15 (1998)


Article DOI: 10.1021/jm9801399
BindingDB Entry DOI: 10.7270/Q2JQ1040
More data for this
Ligand-Target Pair