BDBM50069192 CHEMBL48929::N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide

SMILES Cc1nc(N)ccc1CNC(=O)Cn1cccc(NS(=O)(=O)Cc2ccccc2)c1=O

InChI Key InChIKey=LLEHACLGNXKPPN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069192   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069192(CHEMBL48929 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  26nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069192(CHEMBL48929 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  26nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069192(CHEMBL48929 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  2.00E+4nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069192(CHEMBL48929 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity towards trypsin was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed