BDBM50069454 (1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-propan-1-ol; hydrochloride::CHEMBL540333

SMILES COc1ccc(cc1)[C@H](CN)[C@@H](O)C1CCCCC1

InChI Key InChIKey=OCRYUCYBADHORS-HOTGVXAUSA-N

Data  3 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069454   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKi:  164nMAssay Description:Inhibition of [3H]5-HT reuptake into rat frontal cortex synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKi:  330nMAssay Description:Inhibition of [3H]- NE reuptake into rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKi:  1.46E+3nMAssay Description:Inhibition of [3H]- DA reuptake into rat striatal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKd:  4.31E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKd:  76nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069454((1S,2R)-3-Amino-1-cyclohexyl-2-(4-methoxy-phenyl)-...)
Affinity DataKd:  1.54E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed