BDBM50069769 CHEMBL3407555
SMILES CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1[C@@H]([C@H](C[C@](C)(CC(O)=O)C1=O)c1cccc(Cl)c1F)c1ccc(Cl)cc1
InChI Key InChIKey=HUXQNTCNYMUORT-KVFVXYHUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50069769
Affinity DataIC50: <0.100nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 ( 1 to 188 aa) assessed as inhibition of interaction with human p53 preincubated with compound for...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Binding affinity to MDM2 in human SJSA1 cells assessed as induction of p21 gene level after 7 hrs by qRT-PCR assay in presence of 10% human serumMore data for this Ligand-Target Pair