BDBM50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508

SMILES Oc1cccc(OCCNCc2ccccc2)c1

InChI Key InChIKey=VBTFJGYCISLKEQ-UHFFFAOYSA-N

Data  15 KI

Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50069914   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  3.60nMAssay Description:Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  3.60nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  11nMAssay Description:Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  76nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]-spiperoneMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  76nMAssay Description:Inihibition of [3H]-spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  81nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  81nMAssay Description:Binding affinity towards human cloned dopamine (hD4.4) receptor expressed in CHO cells using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  101nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  101nMAssay Description:Inhibtion of [3H]-spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  115nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  1.78E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  1.78E+3nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069914(3-(2-Benzylamino-ethoxy)-phenol | CHEMBL64508)
Show SMILES Oc1cccc(OCCNCc2ccccc2)c1
Show InChI InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2
Affinity DataKi:  5.29E+3nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair