BDBM50070599 2-Chloro-benzenesulfonic acid 3-(4-guanidino-butoxy)-5-methyl-phenyl ester::CHEMBL287807
SMILES Cc1cc(OCCCCNC(N)=N)cc(OS(=O)(=O)c2ccccc2Cl)c1
InChI Key InChIKey=PVSDNGWLTSTWIU-UHFFFAOYSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50070599
Affinity DataKi: 1.30nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Compound was evaluated for inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+4nMAssay Description:Compound was evaluated for inhibition of TrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+4nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease trypsin using benzoyl-Phe-Val-Arg-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4.90E+4nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease chymotrypsin using suc-Ala-Ala-Pro-Phe-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >4.90E+4nMAssay Description:Compound was evaluated for inhibition of Serine protease chymotrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+5nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease factor Xa using benzoyl-Ile-Glu-Gly-Arg-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+5nMAssay Description:Compound was evaluated for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
3-Dimensional Pharmaceuticals
Curated by ChEMBL
3-Dimensional Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease urokinase using carbobenzyloxy-Phe-Val-Arg-pnitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease plasmin using tosyl-Gly-Pro-Lys-p-nitroanilide as substrateMore data for this Ligand-Target Pair