BDBM50072173 (1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-hexyl-cyclopropanecarboxylic acid::CHEMBL319732

SMILES CCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O

InChI Key InChIKey=HOARSDISRSQYDP-LLQWRFHZSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50072173   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  5.49E+4nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  1.87E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  750nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  122nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  5.61E+4nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  6.25E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072173((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50:  1.25E+4nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 4 (mGluR4) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed