BDBM50072224 (1R,5R,6S)-6-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,2,5]thiadiazol-3-yl]-1-aza-bicyclo[3.2.1]octane::CHEMBL316625

SMILES C(Sc1nsnc1[C@@H]1C[N@]2C[C@@H]1CCC2)C#Cc1ccccc1

InChI Key InChIKey=HCABSDMEPTYQBN-JKSUJKDBSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072224   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50072224((1R,5R,6S)-6-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Affinity DataEC50:  1nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50072224((1R,5R,6S)-6-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Affinity DataIC50:  363nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50072224((1R,5R,6S)-6-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of cAMP in CHO cells expressing human m2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed