BDBM50072626 (S)-2-[2-({(S)-2-[2-(4-Cyano-benzylsulfanyl)-acetylamino]-3-methyl-pentyl}-naphthalen-1-ylmethyl-amino)-acetylamino]-4-methylsulfanyl-butyric acid::2-[2-({2-[2-(4-Cyano-benzylsulfanyl)-acetylamino]-3-methyl-pentyl}-naphthalen-1-ylmethyl-amino)-acetylamino]-4-methylsulfanyl-butyric acid::CHEMBL321981

SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)CSCc1ccc(cc1)C#N

InChI Key InChIKey=WPANQPAWMQHJEJ-VHHLQSIKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072626   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072626((S)-2-[2-({(S)-2-[2-(4-Cyano-benzylsulfanyl)-acety...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-UniversitäT Marburg

Curated by ChEMBL
LigandPNGBDBM50072626((S)-2-[2-({(S)-2-[2-(4-Cyano-benzylsulfanyl)-acety...)
Affinity DataIC50:  5.40nMAssay Description:Inhibitory activity against yeast farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed