BDBM50072740 (6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-amide::(6S,8aS)-N-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-4-oxo-2-(3-phenylpropanoyl)-octahydropyrrolo[1,2-a]pyrazine-6-carboxamide::(S)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [4-guanidino-1-((S)-thiazole-2-carbonyl)-butyl]-amide::CHEMBL324413
SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)CCc1ccccc1)C(=O)c1nccs1
InChI Key InChIKey=LAGUWJUZJRIYRI-UFYCRDLUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50072740
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibitory activity of the compound towards ThrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human ThrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity of the compound towards ThrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against thrombin(FIIa)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory activity against thrombin(FIIa)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory activity against human trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity of the compound towards TrypsinMore data for this Ligand-Target Pair