BDBM50073056 4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide::CHEMBL292759::SB-214111
SMILES COc1ccc(NS(=O)(=O)c2ccc(Br)cc2)cc1N1CCN(C)CC1
InChI Key InChIKey=OZYPUQNRUYTZDI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50073056
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline
Curated by PDSP Ki Database
Glaxosmithkline
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline
Curated by PDSP Ki Database
Glaxosmithkline
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline
Curated by PDSP Ki Database
Glaxosmithkline
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline
Curated by PDSP Ki Database
Glaxosmithkline
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline
Curated by PDSP Ki Database
Glaxosmithkline
Curated by PDSP Ki Database
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4 as total cyclosporin oxidation (1 uM)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cytochrome P450 1A2 activity as caffeine N3 demethylation (500 uM)More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human cytochrome P450 2C19 as S-mephenytoin-4-hydroxylation (100 uM)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human cytochrome P450 2D6 as bufuralol 1''-hydroxylation (10 uM)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory potential of human cytochrome P450 2C9 as tolbutamide methylhydroxylation (100 uM)More data for this Ligand-Target Pair