BDBM50073688 CHEMBL357034::[2-(5-tert-Butyl-1H-indol-3-yl)-ethyl]-methyl-amine

SMILES CNCCc1c[nH]c2ccc(cc12)C(C)(C)C

InChI Key InChIKey=BEPGJIBRVXQULF-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073688   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  0.450nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  1.90nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  6.10nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataEC50:  0.220nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase in a cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed