BDBM50074903 2-[5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen-1-yl)-pyridin-2-yl]-4-pyridin-3-yl-2H-phthalazin-1-one; hydrochloride::CHEMBL536785

SMILES COc1cc2cc(CO)c(CO)c(-c3ccc(nc3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c2cc1OC

InChI Key InChIKey=OKFXGRLQLSKPJJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074903   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074903(2-[5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)
Affinity DataIC50:  8.00E+4nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074903(2-[5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Phosphodiesterase 5 of guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074903(2-[5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Phosphodiesterase 4 from guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50074903(2-[5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 1 of guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed