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BDBM50075255 CHEMBL145501::[1-(2-{2-[(2,4-Dichloro-phenylamino)-methyl]-benzo[b]thiophen-3-yl}-ethyl)-piperidin-4-yl]-dimethyl-amine

SMILES: CN(C)C1CCN(CCc2c(CNc3ccc(Cl)cc3Cl)sc3ccccc23)CC1

InChI Key: InChIKey=NENJOUUKLFZAFH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075255   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))
BDBM50075255
PNG
(CHEMBL145501 | [1-(2-{2-[(2,4-Dichloro-phenylamino...)
Show SMILES CN(C)C1CCN(CCc2c(CNc3ccc(Cl)cc3Cl)sc3ccccc23)CC1
Show InChI InChI=1S/C24H29Cl2N3S/c1-28(2)18-9-12-29(13-10-18)14-11-20-19-5-3-4-6-23(19)30-24(20)16-27-22-8-7-17(25)15-21(22)26/h3-8,15,18,27H,9-14,16H2,1-2H3
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Similars

Article
PubMed
1.70E+3n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Ability to displace [125I]-pPYY from AV12 cell line stably transfected with cloned human neuropeptide Y receptor type 1.


Bioorg Med Chem Lett 9: 475-80 (1999)


Article DOI: 10.1016/s0960-894x(99)00019-0
BindingDB Entry DOI: 10.7270/Q2K35ST3
More data for this
Ligand-Target Pair