BDBM50076428 4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide::CHEMBL38413

SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCC(F)CC2)c2ccccn2)CC1

InChI Key InChIKey=JQSMVIQRTYWIED-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076428   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50076428(4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-metho...)
Affinity DataKi:  0.247nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor by Panlabs assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50076428(4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-metho...)
Affinity DataKi:  0.515nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50076428(4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-metho...)
Affinity DataKi:  1nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed