BDBM50077602 4-[2-(4-Phenyl-butylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL61671

SMILES O=C1Cc2c(N1)cccc2OCCNCCCCc1ccccc1

InChI Key InChIKey=PTTJRNUQRLBAEV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077602   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077602(4-[2-(4-Phenyl-butylamino)-ethoxy]-1,3-dihydro-ind...)
Affinity DataKi:  0.230nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077602(4-[2-(4-Phenyl-butylamino)-ethoxy]-1,3-dihydro-ind...)
Affinity DataKi:  1.90nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077602(4-[2-(4-Phenyl-butylamino)-ethoxy]-1,3-dihydro-ind...)
Affinity DataKi:  2.10nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed