BDBM50077606 6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4-dione::CHEMBL53002

SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C

InChI Key InChIKey=GNENZJCWXXDRKE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50077606   

TargetDNA topoisomerase 3(Bacillus subtilis)
TBA

Curated by ChEMBL
LigandPNGBDBM50077606(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Affinity DataKi:  190nMAssay Description:Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50077606(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Affinity DataKi:  310nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 3(Bacillus subtilis)
TBA

Curated by ChEMBL
LigandPNGBDBM50077606(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50077606(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Affinity DataKi: >3.15E+5nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Escherichia coli)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50077606(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Affinity DataKi: >3.23E+5nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Escherichia coli; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed