BDBM50079715 CHEMBL64237::Tetradecanethioic acid (2,6-diisopropyl-phenyl)-amide

SMILES CCCCCCCCCCCCCC(=S)Nc1c(cccc1C(C)C)C(C)C

InChI Key InChIKey=ZNAMSRLUCLZWRT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50079715   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  281nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  141nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  6nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  130nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  113nMAssay Description:Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  554nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  89nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  137nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed