BDBM50080398 (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-((S)-1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol::2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol::CHEMBL420705::N6-[(S)-1-Methyl-2-phenylethyl]ado (S-PIA)
SMILES C[C@@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InChI Key InChIKey=RIRGCFBBHQEQQH-KFAHYOAQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50080398
Affinity DataKi: 8nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to bovine brainMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]CHA (N6-cyclohexyl adenosine) to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Antagonist binding of 2-chloro-[3H]-adenosine to rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]CHA from adenosine A1 receptor of rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity for Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]-CHAMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity to adenosine A1 receptor in rat whole brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]- (R)-P1A binding to adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat fatMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Affinity for human Adenosine A3 receptor expressed in CHO cellMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat testesMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Evaluated for the binding affinity towards the Adenosine A1 receptor in corpora striata of rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Affinity to Adenosine A3 receptor of rat testis membrane using [3H](R)-PIA with 150 nM DPCPXMore data for this Ligand-Target Pair
Affinity DataKi: 241nMAssay Description:Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranesMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.72E+3nMAssay Description:Binding affinity to A2 adenosine receptor in rat striatal membranes by [3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide)...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.More data for this Ligand-Target Pair
Affinity DataKi: 1.81E+3nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of [3H]- NECA binding to adenosine receptor A2AMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Binding affinity for Adenosine A2 receptor in corpora striata of rats using [3H]NECAMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Evaluated for the binding affinity towards the Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Effect on forskolin-stimulated cyclic AMP production in intact chinese hamster ovary (CHO) cell expressing the human Adenosine A3 receptorMore data for this Ligand-Target Pair