BDBM50081914 5-(3-Heptyloxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL285209
SMILES CCCCCCCOc1cccc(Cc2cnc(N)nc2N)c1
InChI Key InChIKey=ARHDQCNCQPWFCT-UHFFFAOYSA-N
Data 15 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50081914
Affinity DataKi: 131nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
Affinity DataKi: 221nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Leishmania major.More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Salmonella enterica subsp. enterica serovar Typhi)
Pomona College
Curated by ChEMBL
Pomona College
Curated by ChEMBL
Affinity DataKi: 407nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 407nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 407nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coli (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
Affinity DataKi: 407nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
Affinity DataKi: 1.33E+3nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Trypanosoma cruzi.More data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.69E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
Affinity DataKi: 2.69E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.88E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
Affinity DataKi: 2.88E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair