BDBM50082319 (R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-yl]-propan-2-ol; hydrochloride::CHEMBL554228

SMILES O[C@@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=FXLWBYZTEVJBSX-HSZRJFAPSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082319   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  4.64E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  4.08E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed