BDBM50082412 1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-yl-2-propanol::4-phenyl-1-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-yl-2-butanol::CHEMBL114453
SMILES OC(CCc1ccccc1)CN1CCC2(CC1)OCc1c2ccc2ccccc12
InChI Key InChIKey=VDHDMUDOZMDKBK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50082412
Affinity DataKi: 8.30nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Displacement of specific [3H]- 5-HT binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of specific [3H]- citalopram binding to 5-HT uptake site in rat whole cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Stimulation of [35S]- GIPyS binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair