BDBM50082412 1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-yl-2-propanol::4-phenyl-1-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-yl-2-butanol::CHEMBL114453

SMILES OC(CCc1ccccc1)CN1CCC2(CC1)OCc1c2ccc2ccccc12

InChI Key InChIKey=VDHDMUDOZMDKBK-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50082412   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50082412(1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-...)
Affinity DataKi:  8.30nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50082412(1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-...)
Affinity DataKi:  8.30nMAssay Description:Displacement of specific [3H]- 5-HT binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50082412(1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-...)
Affinity DataKi:  10nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50082412(1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-...)
Affinity DataKi:  10nMAssay Description:Displacement of specific [3H]- citalopram binding to 5-HT uptake site in rat whole cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50082412(1-phenyl-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-...)
Affinity DataEC50:  37nMAssay Description:Stimulation of [35S]- GIPyS binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed