BDBM50083121 (R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol::CHEMBL147961

SMILES OC[C@H](NC1CCN(CCCc2c[nH]c3ccc(cc23)-n2cncn2)CC1)c1ccccc1

InChI Key InChIKey=IYKHNVFYEXEGFE-SANMLTNESA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083121   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083121((R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-yl-1H-ind...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083121((R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-yl-1H-ind...)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083121((R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-yl-1H-ind...)
Affinity DataEC50:  7.40nMAssay Description:Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed