BDBM50084135 3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-butyl-phenyl)-methyl]-phenol::CHEMBL151416

SMILES C[C@H]1CN(Cc2ccccc2)CCN1C(c1ccc(cc1)C(C)(C)C)c1cccc(O)c1

InChI Key InChIKey=AHXMJVFHPCQZOY-XYXHBKGXSA-N

Data  3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084135   

TargetMu-type opioid receptor(MOUSE)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084135(3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-...)
Show SMILES C[C@H]1CN(Cc2ccccc2)CCN1C(c1ccc(cc1)C(C)(C)C)c1cccc(O)c1
Show InChI InChI=1S/C29H36N2O/c1-22-20-30(21-23-9-6-5-7-10-23)17-18-31(22)28(25-11-8-12-27(32)19-25)24-13-15-26(16-14-24)29(2,3)4/h5-16,19,22,28,32H,17-18,20-21H2,1-4H3/t22-,28?/m0/s1
Affinity DataIC50: 290nMAssay Description:Agonist activity of the compound was determined using electrically induced smooth muscle contraction of mouse vas deferens.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084135(3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-...)
Show SMILES C[C@H]1CN(Cc2ccccc2)CCN1C(c1ccc(cc1)C(C)(C)C)c1cccc(O)c1
Show InChI InChI=1S/C29H36N2O/c1-22-20-30(21-23-9-6-5-7-10-23)17-18-31(22)28(25-11-8-12-27(32)19-25)24-13-15-26(16-14-24)29(2,3)4/h5-16,19,22,28,32H,17-18,20-21H2,1-4H3/t22-,28?/m0/s1
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibition of [3H]-DAMGO (Tyr-D-Ala-Gly-(Me)-Phe-Gly-ol) binding to Opioid receptor mu 1 using rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084135(3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-...)
Show SMILES C[C@H]1CN(Cc2ccccc2)CCN1C(c1ccc(cc1)C(C)(C)C)c1cccc(O)c1
Show InChI InChI=1S/C29H36N2O/c1-22-20-30(21-23-9-6-5-7-10-23)17-18-31(22)28(25-11-8-12-27(32)19-25)24-13-15-26(16-14-24)29(2,3)4/h5-16,19,22,28,32H,17-18,20-21H2,1-4H3/t22-,28?/m0/s1
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of [3H]-deltorphin binding to Opioid receptor delta 1 using rat brain membranes.More data for this Ligand-Target Pair