BDBM50084338 (2-Benzhydryloxy-ethyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-amine::CHEMBL66112
SMILES Fc1ccc(CCN2CCCC(CNCCOC(c3ccccc3)c3ccccc3)C2)cc1
InChI Key InChIKey=WPCCYICQOQQNOQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50084338
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair