BDBM50084340 CHEMBL417035::[1-(2-Benzhydryloxy-ethyl)-piperidin-3-ylmethyl]-[2-(4-fluoro-phenyl)-ethyl]-amine
SMILES Fc1ccc(CCNCC2CCCN(CCOC(c3ccccc3)c3ccccc3)C2)cc1
InChI Key InChIKey=FECMCOWJDSNXAS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50084340
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 87nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 890nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 364nMAssay Description:Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair