BDBM50085333 CHEMBL163087::Dipropyl-(4-trimethylsilanylethynyl-cyclohex-3-enyl)-amine

SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C

InChI Key InChIKey=VJEWRCWFWRMYOH-UHFFFAOYSA-N

Data  26 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50085333   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  16nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  17nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  23nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  29nMAssay Description:Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2 .Tested for ability to displace the radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  30nMAssay Description:Binding Affinity was tested on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole at t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  47nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  54nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  150nMAssay Description:Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]-SpiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  160nMAssay Description:Binding affinity on High Affinity Site of Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  160nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  640nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  820nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  970nMAssay Description:Binding Affinity on High Affinity Site of Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  1.60E+3nMAssay Description:Dissociation constant of compound on one-site model Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]spiperone at the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  3.80E+3nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding Affinity was tested on low Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]spiperone at the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding Affinity was determined for decoupling of the ternary complex of Compound to Bovine dopamine receptor D2. Tested for ability to displace the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding Affinity of Compound of Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding Affinity was tested on High Affinity Site of Bovine dopamine receptor D1. Tested for ability to displace the radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085333(CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...)
Affinity DataKi: >2.00E+4nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed