BDBM50085678 4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-imidazole::CHEMBL284213

SMILES C1CC(c2cnc[nH]2)c2ccsc2C1

InChI Key InChIKey=BFSPTAYUYXLBEU-UHFFFAOYSA-N

Data  9 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50085678   

TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  0.560nMAssay Description:Binding affinity towards alpha-2D adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  0.560nMAssay Description:In vitro rat alpha-2D adrenergic receptor binding using p-aminoclonidineMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  27nMAssay Description:in vitro alpha-2A adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligandMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  27nMAssay Description:Binding affinity towards Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  99nMAssay Description:Binding affinity towards Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  99nMAssay Description:in vitro alpha-2B adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligandMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  110nMAssay Description:Tested for Binding affinity towards alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  172nMAssay Description:Binding affinity towards alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(RAT)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085678(4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...)
Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1
Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)
Affinity DataKi:  172nMAssay Description:in vitro alpha-2C adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligandMore data for this Ligand-Target Pair