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BDBM50085836 CHEMBL172412::[2-Cyano-5-(furan-3-ylmethoxy)-phenoxy]-o-tolyl-acetic acid

SMILES: Cc1ccccc1C(Oc1cc(OCc2ccoc2)ccc1C#N)C(O)=O

InChI Key: InChIKey=ZOHQPXPUZCOPSH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085836   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
EDNRA


(RAT)
BDBM50085836
PNG
(CHEMBL172412 | [2-Cyano-5-(furan-3-ylmethoxy)-phen...)
Show SMILES Cc1ccccc1C(Oc1cc(OCc2ccoc2)ccc1C#N)C(O)=O
Show InChI InChI=1S/C21H17NO5/c1-14-4-2-3-5-18(14)20(21(23)24)27-19-10-17(7-6-16(19)11-22)26-13-15-8-9-25-12-15/h2-10,12,20H,13H2,1H3,(H,23,24)
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PC sid
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Similars

Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.


J Med Chem 43: 900-10 (2000)


Article DOI: 10.1021/jm990378b
BindingDB Entry DOI: 10.7270/Q2154G73
More data for this
Ligand-Target Pair