BDBM50085852 CHEMBL174229::[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-phenyl-acetic acid

SMILES OC(=O)C(Oc1cc(OCc2ccsc2)ccc1C#N)c1ccccc1

InChI Key InChIKey=AXRWHVQKSIEFTF-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085852   

TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085852(CHEMBL174229 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Show SMILES OC(=O)C(Oc1cc(OCc2ccsc2)ccc1C#N)c1ccccc1
Show InChI InChI=1S/C20H15NO4S/c21-11-16-6-7-17(24-12-14-8-9-26-13-14)10-18(16)25-19(20(22)23)15-4-2-1-3-5-15/h1-10,13,19H,12H2,(H,22,23)
Affinity DataIC50: 70nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair