BDBM50085929 4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-piperidin-4-ol::CHEMBL177624

SMILES OC(CCc1ccccc1)CN1CCC(O)(CC1)c1ccc(O)cc1

InChI Key InChIKey=XLDIBMOCFJDOAH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085929   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50085929(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50085929(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50085929(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50085929(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed