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BDBM50086137 2-p-Tolyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione::CHEMBL279410

SMILES: Cc1ccc(cc1)-n1nc2n(c3ccccc3[nH]c2=O)c1=O

InChI Key: InChIKey=XHVPSVUOSSODBL-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086137   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50086137
PNG
(2-p-Tolyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-...)
Show SMILES Cc1ccc(cc1)-n1nc2n(c3ccccc3[nH]c2=O)c1=O
Show InChI InChI=1S/C16H12N4O2/c1-10-6-8-11(9-7-10)20-16(22)19-13-5-3-2-4-12(13)17-15(21)14(19)18-20/h2-9H,1H3,(H,17,21)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



Universita' di Firenze

Curated by ChEMBL


Assay Description
Binding affinity towards human adenosine A3 receptor expressed in HEK-293 cells in presence of [125I]-AB-MECA at a concentration of 1 uM


J Med Chem 43: 1158-64 (2000)


Article DOI: 10.1021/jm991096e
BindingDB Entry DOI: 10.7270/Q2QR4WBG
More data for this
Ligand-Target Pair
Adenosine A1 receptor


(BOVINE)
BDBM50086137
PNG
(2-p-Tolyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-...)
Show SMILES Cc1ccc(cc1)-n1nc2n(c3ccccc3[nH]c2=O)c1=O
Show InChI InChI=1S/C16H12N4O2/c1-10-6-8-11(9-7-10)20-16(22)19-13-5-3-2-4-12(13)17-15(21)14(19)18-20/h2-9H,1H3,(H,17,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
155n/an/an/an/an/an/an/an/a



Universita' di Firenze

Curated by ChEMBL


Assay Description
Binding affinity towards adenosine A1 receptor of bovine brain membrane in presence of [3H]-CHA at a concentration of 20 uM


J Med Chem 43: 1158-64 (2000)


Article DOI: 10.1021/jm991096e
BindingDB Entry DOI: 10.7270/Q2QR4WBG
More data for this
Ligand-Target Pair