BDBM50087642 CHEMBL163251::N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-2-(1-carbamimidoyl-piperidin-4-yl)-2-phenylmethanesulfonylamino-acetamide; TFA

SMILES NC(=N)N1CCC(CC1)C(NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=XVZUGHXHPQDORQ-OCDPCBSRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087642   

TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087642(CHEMBL163251 | N-[((S)-1-Carbamimidoyl-2-hydroxy-p...)
Affinity DataIC50:  1.10nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087642(CHEMBL163251 | N-[((S)-1-Carbamimidoyl-2-hydroxy-p...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087642(CHEMBL163251 | N-[((S)-1-Carbamimidoyl-2-hydroxy-p...)
Affinity DataIC50:  678nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087642(CHEMBL163251 | N-[((S)-1-Carbamimidoyl-2-hydroxy-p...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed