BDBM50087707 CHEMBL295563::[3-(2,4-Dimethoxy-phenyl)-2,5-dimethyl-3H-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine::[3-(2,4-Dimethoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine

SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1OC

InChI Key InChIKey=YGIHMRSIPWHSFR-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087707   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to the cloned human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataKi:  2.80nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptor (hCRF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50087707(CHEMBL295563 | [3-(2,4-Dimethoxy-phenyl)-2,5-dimet...)
Affinity DataEC50:  142nMAssay Description:Antagonist potency in hCRF1 stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed