BDBM50088174 CHEMBL3427251
SMILES Cc1noc(C)c1[C@@H]1C[C@](C)(N=C(N)S1)c1cc(c(F)cc1F)-c1cncnc1
InChI Key InChIKey=UWUREBMKVJWTPP-PXNSSMCTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50088174
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human H4 cells transfected with APP751 assessed as reduction in amyloidbeta level incubated for 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta 40 or amyloid beta 42 production incuba...More data for this Ligand-Target Pair