BDBM50088537 CHEMBL6251::US10189805, Compound 1
SMILES N[C@@H](CCC(=O)Nc1ccc(cc1)[N+]([O-])=O)C(O)=O
InChI Key InChIKey=WMZTYIRRBCGARG-VIFPVBQESA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50088537
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Affinity DataIC50: 9.54E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation countingMore data for this Ligand-Target Pair
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of ASCT2 (unknown origin)More data for this Ligand-Target Pair
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ASCT2 (unknown origin)-mediated glutamine transportMore data for this Ligand-Target Pair
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Vanderbilt University Institute Of Imaging Science (Vuiis)
Curated by ChEMBL
Affinity DataIC50: 9.54E+5nMAssay Description:The glutamine uptake assays in HEK293 cells were carried out in 96 well plates (CulturPlate-96, Perkin Elmer). Cells were plated at a density of 35,0...More data for this Ligand-Target Pair
TargetAmino acid transporter(Rattus norvegicus)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 7.02E+4nMAssay Description:Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation countingMore data for this Ligand-Target Pair